{"id":2386,"date":"2022-01-20T20:04:22","date_gmt":"2022-01-20T11:04:22","guid":{"rendered":"https:\/\/info.hbn-cl.com\/?p=2386"},"modified":"2022-07-21T00:13:12","modified_gmt":"2022-07-20T15:13:12","slug":"%e3%83%ac%e3%82%a4%e3%83%9c%e3%83%bc%e9%8c%a0","status":"publish","type":"post","link":"https:\/\/info.hbn-cl.com\/?p=2386","title":{"rendered":"\u65b0\u3057\u3044\u7247\u982d\u75db\u6cbb\u7642\u85ac\uff1a\u30ec\u30a4\u30dc\u30fc\u9320\uff08\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53\u4f5c\u50cd\u85ac\uff09"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2452\" src=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/REYVOW-1.jpg\" alt=\"\" width=\"686\" height=\"573\" srcset=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/REYVOW-1.jpg 686w, https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/REYVOW-1-300x251.jpg 300w\" sizes=\"auto, (max-width: 686px) 100vw, 686px\" \/><\/p>\n<h4 style=\"text-align: center;\">\u30bb\u30ed\u30c8\u30cb\u30f3 1F \u53d7\u5bb9\u4f53\u3078\u306e\u9078\u629e\u6027\u3092\u6709\u3059\u308b\u3001\u4e16\u754c\u521d\u306e\u30b8\u30bf\u30f3\u7cfb\u7247\u982d\u75db\u6cbb\u7642\u5264<\/h4>\n<p style=\"text-align: center;\"><strong>\uff12\uff10\uff12\uff12\u5e74\uff16\u6708\uff18\u65e5\u3001\u30ec\u30a4\u30dc\u30fc\u9320\u304c\u767a\u58f2\u3055\u308c\u307e\u3057\u305f\u3002<\/strong><\/p>\n<p style=\"text-align: center;\"><strong>\u85ac\u4fa1\u300050mg\u9320 324.7\u5186\u3001100mg\u9320570.9\u5186\u3000\u3067\u3059\u3002<\/strong><\/p>\n<p>\u5c1a\u3001\u6628\u5e74\u306e4\u6708\u767a\u58f2\u3055\u308c\u305f<a href=\"https:\/\/info.hbn-cl.com\/?p=2215\">\u30a8\u30e0\u30ac\u30eb\u30c6\u30a3<\/a>\u306f\u7247\u982d\u75db\u306e<strong>\u4e88\u9632<\/strong>\u85ac\u3067\u3001\u30ec\u30a4\u30dc\u30fc\u9320\u306f<strong>\u6cbb\u7642<\/strong>\u85ac\u3067\u3059\u3002<\/p>\n<p><span style=\"text-decoration: underline;\">\u8133\u6897\u585e\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u3001\u30c8\u30ea\u30d7\u30bf\u30f3\u3092\u670d\u7528\u3067\u304d\u306a\u3044\u7247\u982d\u75db\u306e\u65b9\u3067\u3082\u670d\u7528\u53ef\u80fd\u3067\u3059\u3002<\/span><\/p>\n<p>\u30ec\u30a4\u30dc\u30fc\u00ae\u9320\u306f\u3001\u30a4\u30fc\u30e9\u30a4\u30ea\u30ea\u30fc\u30fb\u30a2\u30f3\u30c9\u30fb\u30ab\u30f3\u30d1\u30cb\u30fc\u306b\u3088\u308a\u7247\u982d\u75db\u767a\u4f5c\u306e\u6025\u6027\u671f\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305f\u3001\u4e16\u754c\u521d\u306e\u4f4e\u5206\u5b50\u306e<strong>\u9078\u629e\u7684\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong>\u3067\u3059\u3002\u7247\u982d\u75db\u306e\u75c5\u614b\u306b\u306f\u3001\u4e2d\u67a2\u3067\u306e\u75bc\u75db\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3001\u53ca\u3073\u672b\u68a2\u3067\u306e\u4e09\u53c9\u795e\u7d4c\u7cfb\u306e\u904e\u6d3b\u52d5\u304c\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001<strong>\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53<\/strong>\u304c\u8996\u5e8a\u3001\u5927\u8133\u76ae\u8cea\u3001\u4e09\u53c9\u795e\u7d4c\u7cfb\u306e\u795e\u7d4c\u7d30\u80de\u3084\u30b7\u30ca\u30d7\u30b9\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\uff08\u4e0b\u56f3e\uff09\u3001\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53\u306e\u7247\u982d\u75db\u306e\u75c5\u614b\u3078\u306e\u95a2\u9023\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u5264\u306f\u3001\u8840\u6db2\u8133\u95a2\u9580\u901a\u904e\u6027\u3092\u6709\u3057\u3001\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53\u306b\u9078\u629e\u7684\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u4e2d\u67a2\u3067\u306e\u75bc\u75db\u60c5\u5831\u306e\u4f1d\u9054\u3092\u6291\u5236\u3057\u3001\u672b\u68a2\u3067\u306f\u4e09\u53c9\u795e\u7d4c\u304b\u3089\u306e\u795e\u7d4c\u539f\u6027\u708e\u75c7\u3084\u75bc\u75db\u4f1d\u9054\u306b\u95a2\u308f\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff3b\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u907a\u4f1d\u5b50\u95a2\u9023\u30da\u30d7\u30c1\u30c9\uff08CGRP\uff09\u3084\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306a\u3069\uff3d\u306e\u653e\u51fa\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u7247\u982d\u75db\u767a\u4f5c\u306b\u5bfe\u3059\u308b\u4f5c\u7528\u3092\u793a\u3059\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7247\u982d\u75db\u306e\u6025\u6027\u671f\u6cbb\u7642\u85ac\u3068\u3057\u30662019\u5e7411\u6708\u3001\u7c73\u56fd\u306b\u304a\u3044\u3066\u627f\u8a8d\u3092\u53d6\u5f97\u3057\u3001\u60a3\u8005\u3055\u3093\u306b\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u30ec\u30a4\u30dc\u30fc\u306e\u4f5c\u7528\u306e\u30a4\u30e1\u30fc\u30b8\uff1aCGRP\u306e\u653e\u51fa\u3092\u963b\u5bb3\u3059\u308b<\/li>\n<\/ul>\n<p>\u5f15\u7528\uff1a<a href=\"https:\/\/thejournalofheadacheandpain.biomedcentral.com\/articles\/10.1186\/s10194-020-01132-3\">Lasmiditan mechanism of action &#8211; review of a selective 5-HT(1F) agonist.<\/a> Clemow DB,et al. J Headache Pain. 2020 Jun 10;21(1):71.\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2401\" src=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/lamisditan.jpg\" alt=\"\" width=\"684\" height=\"1050\" srcset=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/lamisditan.jpg 684w, https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/lamisditan-195x300.jpg 195w, https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/lamisditan-667x1024.jpg 667w\" sizes=\"auto, (max-width: 684px) 100vw, 684px\" \/><\/p>\n<ul>\n<li>\u30bb\u30ed\u30c8\u30cb\u30f31F\u53d7\u5bb9\u4f53\u306e\u3078\u767a\u73fe\u90e8\u4f4d\u3068\u9078\u629e\u7684\u306b\u53d7\u5bb9\u4f53\u4f5c\u50cd\u3059\u308bLasmiditan<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2404\" src=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/Lasmiditan2.jpg\" alt=\"\" width=\"477\" height=\"305\" srcset=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/Lasmiditan2.jpg 477w, https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/Lasmiditan2-300x192.jpg 300w\" sizes=\"auto, (max-width: 477px) 100vw, 477px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u30c8\u30ea\u30d7\u30bf\u30f3\u88fd\u5264\u306f\u8840\u7ba1\u5185\u76ae\u7d30\u80de5-HT<sub>1B<\/sub>\u53d7\u5bb9\u4f53\u3092\u523a\u6fc0\u3057\u3066\u8840\u7ba1\u304c\u53ce\u7e2e\u3059\u308b\u305f\u3081\u3001\u8133\u6897\u585e\u3084\u5fc3\u7b4b\u6897\u585e\u3001\u8840\u7ba1\u72ed\u7a84\u304c\u3042\u308b\u65b9\u306b\u306f\u7981\u5fcc\u3067\u3057\u305f\u304c\u3001\u3053\u306e\u30ec\u30a4\u30dc\u30fc\u306f<span class=\"rmarker-s\">5-HT<sub>1B<\/sub>\u53d7\u5bb9\u4f53\u3078\u306e\u4f5c\u7528\u304c\u307b\u307c\u7121\u3044\u305f\u3081\u3001\u4eca\u307e\u3067\u30c8\u30ea\u30d7\u30bf\u30f3\u304c\u4f7f\u3048\u306a\u304b\u3063\u305f\u65b9\u306b\u3082\u4f7f\u3048\u308b\u982d\u75db\u6cbb\u7642\u85ac\u3067\u306f\u306a\u3044\u304b\u3068\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p><strong>\u7528\u6cd5\u7528\u91cf<\/strong>\uff1a\u901a\u5e38\u3001\u6210\u4eba\u306b\u306f\u30e9\u30b9\u30df\u30b8\u30bf\u30f3\u3068\u3057\u30661\u56de100 mg\u3092\u7247\u982d\u75db\u767a\u4f5c\u6642\u306b\u7d4c\u53e3\u6295\u4e0e\u3059\u308b\u3002<br \/>\n\u305f\u3060\u3057\u3001\u60a3\u8005\u306e\u72b6\u614b\u306b\u5fdc\u3058\u306650 mg\u53c8\u306f200 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2459\" src=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/5cff00b8cd97fbe584fd185e34ae463c.jpg\" alt=\"\" width=\"755\" height=\"227\" srcset=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/5cff00b8cd97fbe584fd185e34ae463c.jpg 755w, https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/5cff00b8cd97fbe584fd185e34ae463c-300x90.jpg 300w\" sizes=\"auto, (max-width: 755px) 100vw, 755px\" \/><br \/>\n\u53c2\u8003\u8cc7\u6599\uff1a<br \/>\n\u3000\u30ec\u30a4\u30dc\u30fc\u9320\u3000<a href=\"https:\/\/www.daiichisankyo.co.jp\/files\/news\/pressrelease\/pdf\/202201\/20220120_J.pdf\">\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9<\/a><br \/>\n\u3000\u30ec\u30a4\u30dc\u30fc\u9320\u3000<a href=\"https:\/\/info.hbn-cl.com\/wp-content\/uploads\/2022\/01\/df93926b6d6fc9d16d7bdb5d0e7cb98f.pdf\">\u30d1\u30f3\u30d5\u30ec\u30c3\u30c8<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30bb\u30ed\u30c8\u30cb\u30f3 1F \u53d7\u5bb9\u4f53\u3078\u306e\u9078\u629e\u6027\u3092\u6709\u3059\u308b\u3001\u4e16\u754c\u521d\u306e\u30b8\u30bf\u30f3\u7cfb\u7247\u982d\u75db\u6cbb\u7642\u5264 \uff12\uff10\uff12\uff12\u5e74\uff16\u6708\uff18\u65e5\u3001\u30ec\u30a4\u30dc\u30fc\u9320\u304c\u767a\u58f2\u3055\u308c\u307e\u3057\u305f\u3002 \u85ac\u4fa1\u300050mg\u9320 324.7\u5186\u3001100mg\u9320570.9\u5186\u3000\u3067\u3059\u3002 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